Basic Sciences Symposium
Information
Topic: Spatial Biology in Benign and Malignant Urologic Disease
Symposium Goal: Benign and malignant prostate diseases display high cellular heterogeneity. While single cell assays provide an objective profile of cells within a tumor, they do so by necessarily destroying tissue architecture. Spatial profiling technologies utilize intact fixed or frozen specimens that enable a link between phenotype and genotype. Recent advances in spatial epigenomics are providing new insights into epigenetic priming, differentiation and gene regulation with implications for cellular anatomy, tumor staging and grading in urologic disease.
Funding for this conference was made possible (in part) by 1 R13 DK139769 -01 from NIDDK. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.