029IC - New AUA Guideline (2024): Salvage Therapy for Prostate Cancer

Learning Objectives
1. Identify and effectively interpret the optimal timing of salvage radiation therapy following radical prostatectomy, considering the factors that can influence this decision in a clinical context.
2. Develop an understanding of which patients should receive ADT alongside salvage radiation therapy following radical prostatectomy, and how to appropriately decide the duration of ADT for patients.
3. Identify and analyze the use of risk stratification tools and next-generation imaging techniques for guiding treatment decisions and monitoring in patients with biochemical recurrence following primary therapy.
4. Evaluate the role and benefits of advanced treatment options such as intensified systemic therapy and metastasis-directed therapy.
5. Evaluate and understand the indications, efficacy, and potential complications of different salvage local therapies, such as salvage prostatectomy, radiotherapy and cryotherapy, for patients with local recurrence following primary radiation therapy.

Course Description:The course details the 2024 AUA Guidelines for salvage therapy following initial treatment of localized prostate cancer, focusing on integral aspects of salvage treatments, risk stratification and advanced imaging. Participants will gain insights into the timing and appropriate use of salvage radiation therapy with or without androgen deprivation therapy (ADT), the use of risk stratification tools and the application of next-generation imaging in patients with biochemical recurrence. Participants will learn about the latest data supporting optimizing cancer control based on key patient and tumor factors. Key aspects of the course include mastering the interpretation of biomarkers and imaging techniques for accurate detection and monitoring of recurrent prostate cancer. We also emphasize the vital role of shared decision-making in clinical practice, considering patients’ preferences and quality of life. The course aims to equip health care professionals with the necessary knowledge and practical skills to improve patient outcomes in managing recurrent prostate cancer.